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Loren Miller commented on Loren Miller's group Quote Of The Day
"Christian morality is the morality of slaves. -- Friedrich Wilhelm Nietzsche Precisely. Virtually…"
12 hours ago
Loren Miller commented on Loren Miller's group Quote Of The Day
"Dear Joan!  Your mind is many things, but "simple is NOT one of them!  That's…"
12 hours ago
Richard Levison left a comment for Idalia Lopez
""Happy Birthday!""
13 hours ago
Stephen Brodie commented on Loren Miller's group Quote Of The Day
"“If I had to choose between betraying my country and betraying my friend, I hope I should…"
14 hours ago
Joan Denoo commented on Loren Miller's group Quote Of The Day
"I am way behind reading this string and I find it contains great jewels too precious to let go. I…"
15 hours ago
Chris B commented on Loren Miller's group Quote Of The Day
"Joan, many people have trouble reading Shakespeare, because they know that there are meanings and…"
16 hours ago
Joan Denoo commented on Loren Miller's group Quote Of The Day
"Loren, your Bertrand Russell quote, including, "The infliction of cruelty with a good…"
16 hours ago
Joan Denoo commented on Loren Miller's group Quote Of The Day
"Stephen, I generally do not read Shakespeare  because he is too complex for my simple…"
16 hours ago
Joan Denoo commented on Loren Miller's group Quote Of The Day
"Loren, another strong statement, " It was during recovery from her (Ruth Hurmence…"
16 hours ago
Mrs.B commented on Loren Miller's group Quote Of The Day
"Agreed. It's just a book, & I will not live my life according to a book."
16 hours ago
Mrs.B commented on Loren Miller's group Quote Of The Day
"No, Joan, anything I've found doesn't seem to fit."
16 hours ago
Joan Denoo commented on Loren Miller's group Quote Of The Day
"Loren Miller on July 13, 2021 at 6:10am you wrote:  If you're going to dignify the claim…"
16 hours ago
Joan Denoo commented on Loren Miller's group Quote Of The Day
"Mrs.B, I like your comment, "Prayers cannot correct what it couldn't prevent." I am…"
17 hours ago
Joan Denoo commented on Loren Miller's group Quote Of The Day
"Loren, I agree,  Something which does not exist cannot help us, but chronic dependence on…"
17 hours ago
Joan Denoo commented on Loren Miller's group Quote Of The Day
"Loren, "Faith doesn't care whether something is actually TRUE or not." That is…"
17 hours ago
Joan Denoo commented on Loren Miller's group Quote Of The Day
"Grinning Cat, I love your comment about women and choice and the flowchart! Thanks!"
17 hours ago
Mrs.B commented on Loren Miller's group Quote Of The Day
"I liked it. To the point."
yesterday
Loren Miller commented on Loren Miller's group Quote Of The Day
"Most excellent, Mrs. B!"
yesterday
Mrs.B commented on Loren Miller's group Quote Of The Day
yesterday
Stephen Brodie commented on Sydni Moser's group Coffee Break
"Hail smashes through car windscreens & conservatory roofs amid 30c heatwave in extreme UK…"
yesterday

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Drug Reverses Age-Related Mental Decline Within Days, Suggesting Lo...

Research in mice indicates that age and trauma related cognition deficits are potentially reversible.

"... animals who received small daily doses of ISRIB during the three-day training process were able to accomplish the task as well as youthful mice—and much better than animals of the same age who didn’t receive the drug.

The mice who had received brief ISRIB treatment three weeks before still performed at youthful levels, while untreated mice continued to struggle.

The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after traumatic brain injury (TBI), reverse cognitive impairments in Down Syndrome, prevent noise-related hearing loss, fight certain types of prostate cancer, and even enhance cognition in healthy animals.

ISRIB ... works by rebooting cells’ protein production machinery after it gets throttled by one of these stress responses – a cellular quality control mechanism called the integrated stress response (ISR; ISRIB stands for ISR InhiBitor). 

The ISR normally detects problems with protein production in a cell—a potential sign of viral infection or cancer-promoting gene mutations—and responds by putting the brakes on cell’s protein-synthesis machinery. This safety mechanism is critical for weeding out misbehaving cells, but if stuck in the ‘on’ position in a tissue like the brain, it can lead to serious problems, as cells lose the ability to perform their normal activities,..." [order changed]

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Replies to This Discussion

That would be a real breakthrough.

It would be huge! Hopefully available affordably to all, not just a self-perpetuating elite.

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