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Mrs.B replied to Loren Miller's discussion God Comes Out as Pro-Choice (Betty Bowers) in the group Freethought and Funny Bones
"Would have been something else......"
7 hours ago
Mrs.B commented on Sydni Moser's group Coffee Break
"Exactly the same here, Kurt. We've had several disastrous fire seasons, as well as…"
7 hours ago
Andy Stout replied to Loren Miller's discussion God Comes Out as Pro-Choice (Betty Bowers) in the group Freethought and Funny Bones
"If only Mary had an abortion..."
8 hours ago
Davy commented on Sydni Moser's group Coffee Break
"Ian what you are witnessing is the reasons why cultures that form civilisations based upon…"
9 hours ago
Ian Mason commented on Sydni Moser's group Coffee Break
"Extreme weather but mediocre government and inadequate responses. Nobody wants to be bold, except…"
13 hours ago
Loren Miller commented on Loren Miller's group Quote Of The Day
"Human decency is not derived from religion. It precedes it. -- Christopher Hitchens Our forebears…"
13 hours ago
Kurt Neuleuf commented on Sydni Moser's group Coffee Break
"Summer in Australia is going to be fun. extreme firestorms and flooding has been forecast  for…"
13 hours ago
Mrs.B commented on Sydni Moser's group Coffee Break
"Equipment & the personnel to run it. "
18 hours ago
Chris B commented on Sydni Moser's group Coffee Break
"Yes, but your enormous country is harder to monitor, I'd think, and to get the equipment and…"
18 hours ago
Mrs.B commented on Sydni Moser's group Coffee Break
"But we're loaded with lakes & rivers."
18 hours ago
Chris B commented on Sydni Moser's group Coffee Break
"This is a small country with plenty of open water, so fires are much easier to contain. Canada…"
18 hours ago
Mrs.B commented on Sydni Moser's group Coffee Break
"A worry, nonetheless."
20 hours ago
Ian Mason commented on Sydni Moser's group Coffee Break
"Correction: the rain MIGHT start today, in some places, perhaps. Temps at 30c again might start…"
20 hours ago
Mrs.B commented on Sydni Moser's group Coffee Break
"Big, small or otherwise, fires are frightening."
20 hours ago
Chris B commented on Sydni Moser's group Coffee Break
"The first drop of rain has yet to fall, but the clouds look nice. Fires are going on but not on a…"
20 hours ago
Mrs.B commented on Sydni Moser's group Coffee Break
"How is your fire situation there?"
20 hours ago
Stephen Brodie commented on Sydni Moser's group Coffee Break
"We are due some thunder and lightning with perhaps some heavy showers by Wednesday. "
20 hours ago
Ian Mason commented on Sydni Moser's group Coffee Break
"Long may it rain, Chris. We're due to get some in DK about Thursday."
20 hours ago
Ian Mason commented on Sydni Moser's group Coffee Break
"Born-to-money indifference, Stephen. And as long as the stupid proles of the world keep slogging…"
20 hours ago
Mrs.B commented on Sydni Moser's group Coffee Break
"A spokesperson for the BC Wildfire Service says 80 per cent of the 212 new fires sparked across the…"
20 hours ago

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Drug Reverses Age-Related Mental Decline Within Days, Suggesting Lo...

Research in mice indicates that age and trauma related cognition deficits are potentially reversible.

"... animals who received small daily doses of ISRIB during the three-day training process were able to accomplish the task as well as youthful mice—and much better than animals of the same age who didn’t receive the drug.

The mice who had received brief ISRIB treatment three weeks before still performed at youthful levels, while untreated mice continued to struggle.

The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after traumatic brain injury (TBI), reverse cognitive impairments in Down Syndrome, prevent noise-related hearing loss, fight certain types of prostate cancer, and even enhance cognition in healthy animals.

ISRIB ... works by rebooting cells’ protein production machinery after it gets throttled by one of these stress responses – a cellular quality control mechanism called the integrated stress response (ISR; ISRIB stands for ISR InhiBitor). 

The ISR normally detects problems with protein production in a cell—a potential sign of viral infection or cancer-promoting gene mutations—and responds by putting the brakes on cell’s protein-synthesis machinery. This safety mechanism is critical for weeding out misbehaving cells, but if stuck in the ‘on’ position in a tissue like the brain, it can lead to serious problems, as cells lose the ability to perform their normal activities,..." [order changed]

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Replies to This Discussion

That would be a real breakthrough.

It would be huge! Hopefully available affordably to all, not just a self-perpetuating elite.

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