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In a tale of reality surpassing fiction, a spectacular case of horizontal gene transfer (transfer of genes between different, unrelated species) has been reported in the Malaysian parasitic plant, Rafflesia cantleyi. Rafflesia is also known as the corpse flower because of its putrid, pungent smell. Its flowers are the largest single flowers in the world; the strange looking, leathery petals can reach close to 3 feet across. The plant is an obligate parasite that exists entirely within the host's tissues, as strands, except for the very visible flower. The host are vines of the genus Tetrastigma. Flowers take months to develop and last only a few days.  Horizontal gene transfer is rather frequent in bacteria but rare in other organisms. When Harvard scientists started to study Rafflesia in the context of the evolution of parasitism in plants, they noticed an odd gene that looked more like a gene in the host vine than to a similar gene in relatives of Rafflesia. The immediate hypothesis was horizontal gene transfer: the parasite had stolen the gene from its host. They then sequenced all of the active genes of both the corpse flower and the vine and they found that an astonishing 2% of its active genome was stolen from the host! Another third of Rafflesia‘s own genes have evolved to look more like the vine genes. In this way, the relationship between these two plants has become truly intimate. This rate of horizontal gene transfer had previously been seen only in bacteria. Given the large numbers of parasite species on our planet, it is possible that this type of gene thievery has occurred in other parasite-host pairs. 

Parasitic flower pirates genes from its host

Rafflesia cantleyi, perhaps better known as the corpse flower for its pungent scent, steals everything from its host. Though each blossom can be in excess of three feet across, the massive buds cannot support themselves, and have no leaves, stalks or true roots. Instead, they rely entirely upon their vine host,Tetrastigma rafflesiae, for survival. Harvard researchers have now discovered that food and water aren’t the only things the corpse flowers steal – over the course of evolutionary history, Rafflesia has also stolen Tetrastigma‘s genes.

The corpse flower and its host have a very intimate relationship. From the start, Rafflesia burrows into the Tetrastigma‘s tissues, growing as thread-like strands in direct contact with the surrounding vine’s cells. They are so dependant on their host that the corpse flowers have even lost the ability to make chlorophyll, a requirement for photosynthesis, and thus defy the very nature of being a plant by being unable to produce food from sunlight. These parasites feed off their host vines, growing and growing until they finally erupt, dramatically if briefly, into large, rubbery flowers that stinks like rotting flesh.

Somehow, after generations and generations of intimate contact between parasite and host, Rafflesia has ended up with more than the usual parasitic spoils. As a new study published today in BMC Biology reveals, the parasite expresses dozens of genes that it has co-opted from its host.

The passage of genes from distant lineages, such as the corpse flower and its vine host, is known as horizontal gene transfer. Though common in bacteria (e.g. the transfer of antibiotic resistance), it is much rarer in plants and animals, and we still don’t fully understood how it occurs.

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Tags: evolution, flower, gene, parasite, transfer

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